
Merrill's Roxy Cinema, Burlington Vermont
On Thursday evening, February 11th at 6:30 PM, at the Leonard Nimoy Thalia Theatre in New York City, a new film called “To Age or Not to Age” will be shown for the first time. Immediately after the screening filmmaker Robert Kane Pappas (“Orwell Rolls in his Grave”) will lead a panel discussion featuring three of the ...most renowned and electrifying experts in the field of molecular biology and aging: Dr. Leonard P. Guarante , M.I.T., Aubrey de Gray, Methuselah Foundation, and Dr. Robert Butler, Pulitzer Prize winning author of Why Survive? (1975), and founding director of the National Institute on Aging. They will come together to debate and confront the movie’s fundamental assumption – that science’s ability to halt virtually all degenerative infirmities related to aging is here now, and that there is no reason why life expectancy shouldn’t exponentially lengthen, almost immediately. Simply stated, evolution as we generally think of it is speeding up and overtaking he ravages of disease.
As 20th century man conquered the boundaries once fixed by the physical realities of time and distance the question many visionaries asked was, “What if time itself could be extended, if we could live longer, if we could double the age of man?” It seemed a crazy ambition, but it was exactly what the scientists and researchers of the 20th Century accomplished. They had brought the average Life Span from 42 in 1900 to over 80 in just a hundred years.
Less than twenty years ago two students of Dr. Leonard Guarante left some yeast cells chilling over winter break in 1991. When they returned they were surprised to find to find a few had actually survived. In time the caloric restriction they had experienced was understood to trigger an important enzyme in the body, one which had a key role to play in orchestrating the behavior of energy producing processes in the cell. In evolutionary terms, this ensured that in times of stress (e.g. food shortage) fundamental cell processes were being optimized to keep the creature youthful and fertile for longer periods.
As ever greater insights were gained into the metabolic effects caloric restriction triggered, scientists exploring the “French Paradox”, the positive effects of red wine on a high-fat diet, discovered a natural agent in the skins of red grapes, Resveratrol, which produced the same effect in mice as caloric restriction but without the gnawing hunger. In the last three years, since the first wave of exposure in late 2006 was triggered by the report – in a famous study by David Sinclair of Harvard - that this Resveratrol had kept fat mice healthy and youthful and extended their lives by phenomenal amounts, ever more far reaching studies have been conducted showing beneficial links between Resveratrol therapies and the remission (and not just the prevention) of cancer and diabetes.
The discovery is both elegant and simple – disease and aging are often one and the same thing. A body whose cellular activity is slowing down and producing errors in cell division is a welcome host for the illnesses. Therefore, keeping the individual cells in clean working order (i.e. “youthful”) will produce greater resistance to these diseases (including cancer, heart disease, osteoporosis, diabetes and neurodegeneration) and lead to a longer, healthier life. Given the long history of elixirs and snake-oil that promised eternal youth and perfect health, professional scientists hesitate to extrapolate too much based on the studies so far. (The film also pries open the complex politics and procedures of the scientific/medical establishments – a theme worthy of a film entirely in its own right.) Nonetheless, the excitement of these dedicated researchers is palpable. They know something big is coming our way. After seeing this film, you’ll know it, too.
Thursday, February 11th may well become an historic evening and a life-changing experience to anyone who witnesses it.
Time:6:30PM Thursday, February 11th
Location:A one-night LIVE event

Jim Ramey Thanks for showing Rethink Afghanistan today. I for one really appreciate all the community events that you all do.

Merrill's Roxy Cinema, Burlington Vermont
With Falstaff, Verdi bid a magnificent farewell to opera. He chose, however, a genre that he wasn't familiar with: the comic opera. His librettist, Boito, gave Verdi a text, adapted from a Shakespeare play, that allowed him to express all his skills and power, giving the musicians as important a role as the characte...rs. Verdi brought something new to opera at a time when his prior works ha already become classics. This last Verdi opera was first played in front of an enthusiastic Milanese public and ended Verdi's work on a happy note.
To interpret the title role, Ruggero Raimondi, a masterful actor and exceptional artist with a powerful and colorful voice, comes back to Liege for the inauguration of the Royal Opera House. Paolo Arrivabeni conducts this phenomenal production.
Time:1:00PM Sunday, January 31st
Location:Verdi's magnificent farewell

Merrill's Roxy Cinema, Burlington Vermont Don Giovanni, probably Mozart’s most famous opera, is the opening production of the Festival in 2008. Following his successful production of Le nozze di Figaro in Salzburg, German stage director Claus Guth is preparing his second Da Ponte opera. In the title role British baritone Christopher Maltman, Winner of the Lied...er Prize at the 1997 Cardiff Singer of the World Competition will be making his first appearance in Salzburg in an opera production. Annette Dasch, highly celebrated last season as Armida, takes the role of Donna Anna. Bertrand de Billy, Anna Netrebko´s favourite conductor, directs the Vienna Philharmonic. Dorothea Röschmann, particularly renowned for her interpretation of the great Mozart roles, sings the Donna Elvira and Erwin Schrott appears as Leporello.
Time:1:00PM Sunday, January 17th
Location:the Roxy

Bill Jarvis Happy New Years!!!

Merrill's Roxy Cinema, Burlington Vermont wishes you and your family a prosperous and peaceful New Year - thank you for supporting us in the last decade!
















