The Society for Biological Engineering (SBE), an AIChE Technological Community, is a global organization of leading engineers and scientists dedicated to advancing the integration of biology with engineering.
Information
- Location:
- New York, NY
Events
2 upcoming eventsSee All
- Molecular Bioprocessing as a N...
New York
Tuesday, March 2 at 2:00pm - SBE's Second International Con...
Boston, MA
Sunday, May 2 at 5:30pm
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ConferencesCreated about 5 months ago
Wall PhotosCreated about 5 months ago
Society for Biological Engineering (SBE)
Dr. John Dordick, Howard P. Isermann Professor of Chemical and Biological Engineering, and Biology; Director, Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic Institute
Tuesday, March 2, 2010 at 2:00-3:00PM EDT
This webinar is FREE for SBE members and $49.00 for non-members.
About this Webinar
T...he drug discovery process is expensive and often inefficient. With the emergence of genomic and proteomic information, the growth of critical molecular targets is rapid. Nevertheless, the development of active, selective, and safe drug candidates (small molecule or biopharmaceutical) has not kept pace with such advances. For small molecules, a core problem is the lack of high-throughput and accurate methodologies for ADME/Tox, which forces comprehensive toxicology studies to be performed only on later stage lead compounds and preclinical candidates. For biopharmaceuticals, the ability to accurately reproduce the human protein with correct posttranslational modification is limited by lack of knowledge of cellular machinery and then the efficient scale up of protein production and purification. Professor Dordick will detail his research in the design and optimization of high-throughput, microscale discovery and development platforms and the emergence of using bioprocessing strategies at early stages of drug discovery.
Jonathan S. Dordick Biosketch
Jonathan S. Dordick received his B.A. degree in Biochemistry and Chemistry from Brandeis University and his Ph.D. in Biochemical Engineering from the Massachusetts Institute of Technology. He has held chemical engineering faculty appointments at the University of Iowa (1987-1998), where he also served as the Associate Director of the Center for Biocatalysis and Bioprocessing, and Rensselaer Polytechnic Institute (1998-present) where he is the Howard P. Isermann Professor of Chemical and Biological Engineering and Professor of Biology. In 2008 he took over as Director of Rensselaer’s Center for Biotechnology & Interdisciplinary Studies. Prof. Dordick has received numerous awards, including the 2007 Marvin J. Johnson Award, the 2007 Elmer Gaden Award, the 2003 International Enzyme Engineering Award, the 1998 Iowa Section Award of the American Chemical Society, and an NSF Presidential Young Investigator Award in 1989. He was elected as a Fellow of the American Association for the Advancement of Science in 2004 and a Fellow of the American Institute of Medical and Biological Engineers in 1996. He presently serves on the Scientific Advisory Boards for several biotechnology companies and venture capital firms. Dr. Dordick was a cofounder of EnzyMed, Inc. a pharmaceutical and agrochemical discovery company acquired by Albany Molecular Research in 1999, and is a cofounder of Solidus Biosciences, Inc. a venture-stage human drug and cosmetics toxicology company. Dr. Dordick has published over 250 papers and is an inventor/co-inventor on 32 patents and patent applications.
For more information, please go here:
http://www.aiche.org/SBE/Education/Webin
Time:2:00PM Tuesday, March 2nd
Location:New York
Society for Biological Engineering (SBE)
Register now! The Annual Event of American Institute for Medical and Biological Engineering (AIMBE) will be held on February 21-23, 2010 at the Mandarin Oriental Hotel in Washington DC. For more info, go here, https://www.netforumondemand.com/eWeb/Dy
www.netforumondemand.com
Society for Biological Engineering (SBE)
Dr. David Schaffer, Professor of Chemical Engineering, Department of Bioengineering, and the Helen Wills Neuroscience Institute, Co-Director, Berkeley Stem Cell Center, University of California, Berkeley
Thursday, January 21 at 2010, 2-3 PM EST
This webinar is free for SBE members and $49.00 for non-members.
Register Now...!
https://www2.aiche.org/SolutionSite/defa
About this Webinar
Stem cells are defined by their capacities for self-renewal and differentiation into one or more cell lineages, and these processes are regulated by signals from the stem cell microenvironment, or niche, in various tissues throughout organismal development and adulthood. These niches control cell function by presenting complex, regulatory signals including soluble small molecules and proteins, extracellular matrix (ECM) signals, and mechanical cues. There has been considerable progress in studying soluble signal regulation of stem cell function, but comparatively less work has been focused on investigating the “solid phase” of the microenvironment, in large part due to experimental complexities in studying large matrix and other proteins. Recent work demonstrates that bioactive, synthetic materials (i.e., matrices, scaffolds, or culture substrates) can be harnessed to emulate and thereby study the effects of solid phase, or biophysical, signals on stem cell function. We have harnessed biomaterials to investigate a number of aspects of the stem cell microenvironment and have found that extracellular mechanical properties, or stiffness, can profoundly impact neural stem cell self-renewal and differentiation into neurons vs. glia, and mechanistic analysis implicates Rho GTPases as key “mechanotransducers” in this process. Furthermore, immobilization of biochemical signals in the solid phase of a natural niche, including extracellular matrix motifs as well as matrix-binding growth factors, can lead to nanoscale organization of these signals that can modulate signal transduction by controlling cellular receptor clustering. We have developed a hybrid system composed of growth factors oligomerized with a synthetic material and find that nanoscale organization of signaling molecules can profoundly modulate their bioactivity and potency, for example in regulating the proliferation of neural stem cells and the neuronal differentiation of human embryonic stem cells. Finally, we have found that the combinatorial presentation of different motifs from individual extracellular matrix proteins from a material can generate synthetic systems capable of supporting the self-renewal and differentiation of both neural stem cells and human embryonic stem cells, thereby enabling the dissection of the ECM into key individual signals necessary to support stem cell function. Biomimetic materials therefore represent systems that can be used to study principles by which the solid phase of a stem cell microenvironment regulates cell function, as well as offer safe and scaleable systems to precisely control stem cell function for biotechnological and biomedical application.
David Schaffer Biosketch
David Schaffer is a Professor of Chemical Engineering, Bioengineering, and Neuroscience at University of California, Berkeley, where he also serves as the Co-Director of the Berkeley Stem Cell Center. He graduated from Stanford University with a B.S. degree in Chemical Engineering in 1993. Afterward, he attended Massachusetts Institute of Technology and earned his Ph.D. also in Chemical Engineering in 1998 with Professor Doug Lauffenburger. Finally, he did a postdoctoral fellowship in the laboratory of Fred Gage at the Salk Institute for Biological Studies in La Jolla, CA before moving to UC Berkeley in 1999. At Berkeley, Dr. Schaffer applies engineering principles to enhance stem cell and gene therapy approaches for neuroregeneration. This work includes mechanistic investigation of stem cell control, as well as molecular evolution and engineering of viral gene delivery vehicles. David Schaffer has received an NSF CAREER Award, Office of Naval Research Young Investigator Award, Whitaker Foundation Young Investigator Award, and was named a Technology Review Top 100 Innovator. He was also awarded the American Chemical Society BIOT Division Young Investigator Award in 2006, the Biomedical Engineering Society Rita Shaffer Young Investigator Award in 2000, and was elected to the College of Fellows of the American Institute of Medical and Biological Engineering in 2008.
For more information, go here http://www.aiche.org/SBE/Education/SBEwe
Time:2:00PM Thursday, January 21st
Location:New York
Society for Biological Engineering (SBE) CALL FOR PAPERS
Location:Boston, MA
Time:5:30PM Sunday, May 2nd
www.boston.com
This ‘will empower the scientific community to explore the potential of stem cell research,’ NIH chief Francis Collins said.
www.aiche.org
SBE is currently sponsoring a $1000 award for the Best Use of a Biological Reaction to Power a Car during this year' s Chem-E-Car competition.
Society for Biological Engineering (SBE) Winners for 2009 are Wei-Shou Hu and Miranda Gek Sim Yap.
www.aiche.org
The purpose of this award is to recognize an SBE member for his or her dedication and service to the profession of biological engineering and to the Society for Biological Engineering in particular.
Society for Biological Engineering (SBE)
AIChE's Society for Biological Engineering (SBE) has awarded its fifth
annual James E. Bailey Award to Dr. James C. Liao for advances in
metabolic research. Liao is the Chancellors Professor at the
University of California, Los Angeles. He has made major contributions
to biochemical engineering with his theoretical and hi...s experimental
work, and has an international reputation that extends well beyond the
chemical engineering community.
www.aiche.org
Welcome to the AIChE - the on-line home of the American Institute of Chemical Engineers. View the biological engineering press releases and articles.
Society for Biological Engineering (SBE)
Society for Biological Engineering (SBE) has awarded its fifth
annual James E. Bailey Award to Dr. James C. Liao for advances in
metabolic research. Liao is the Chancellor s Professor at the
University of California, Los Angeles. He has made major contributions
to biochemical engineering with his theoretical and his exper...imental
work, and has an international reputation that extends well beyond the
chemical engineering community.
www.aiche.org
Welcome to the AIChE - the on-line home of the American Institute of Chemical Engineers. View the biological engineering press releases and articles.
Society for Biological Engineering (SBE)
A Bottom Up Approach to Systems Biotechnology – Lessons Learned from Bacterial Signal Transduction
Dr. William E. Bentley, Robert E. Fischell Distinguished Professor, Chair, Fischell Department of Bioengineering, University of Maryland
Tuesday, December 8, 2009 at 2:00-3:00 PM EDT
This webinar is free for SBE members and ...$49.00 for non-members.
About this Webinar
Bacterial quorum sensing offers an interesting viewpoint from which to study and control cell phenotype. Through the perception of signal molecules (e.g., AHL, AI-2) and their transduction, bacteria coordinate their behavior and act as multicellular units. This coordination is responsible for establishing virulence among a variety of pathogens. A combination of negative (auto-regulation) and positive feedback mechanisms that control the flow of information can be examined by separating the network architecture into sub-networks. Biofabricated devices that report on signaling events are constructed to elucidate cell-cell communication and serve as a foundation upon which to develop new drugs and/or screen for pathogenic phenotype. Using bottom up approaches such as those we have developed will improve our chances to sense and intercept communication in pathogenic bacteria and prevent the spread of infectious diseases.
William E. Bentley Biosketch
WILLIAM E. BENTLEY is the Robert E. Fischell Distinguished Professor of Engineering and founding Chair of the Fischell Department of Bioengineering. He is also appointed in the Department of Chemical and Biomolecular Engineering at the University of Maryland, College Park and the Center for Biosystems Research of the University of Maryland Biotechnology Institute. Dr. Bentley received his undergraduate (BS, ’82) and Master of Engineering degrees (’83) from Cornell University and his PhD (’89) from the University of Colorado, Boulder, all in chemical engineering. At Maryland since 1989, Dr. Bentley has focused his research on the development of molecular tools that facilitate the expression of biologically active proteins, having authored over 180 related archival publications. Recent interests are on deciphering and manipulating signal transduction pathways, including those of bacterial communication networks, for altering cell phenotype. He has served on advisory committees and panels for the NIH, NSF, DOD, DOE, USDA, and several state agencies. He has mentored over 25 PhDs, some of whom are academics at: Cornell (x2), University of Colorado, Clemson, University of Connecticut, Tufts, Postech (Korea), and Tsing-Hua (Taiwan). He co-founded a protein manufacturing company, Chesapeake PERL, based on insect larvae as mini bioreactors. Dr. Bentley is a Fellow of the AAAS and AIMBE and is an elected member of the American Academy of Microbiology.
For more information, please visit:
http://www.aiche.org/SBE/Education/Webin
Lessons Learned from Bacterial Signal Transduction
Time:2:00PM Tuesday, December 8th
Location:online
Society for Biological Engineering (SBE)
SBE User's Guide for the Annual Meeting
The SBE User’s Guide highlights all of the bio-related sessions happening during the AIChE Annual Meeting in Nashville, TN. Check it out here.
bit.ly
Society for Biological Engineering (SBE)
Bioengineering Highlights at the AIChE Annual Meeting
The AIChE Annual Meeting is on November 8-13, 2009 in Nashville, TN. The Society for Biological Engineering is hosting and cosponsoring a number of exciting events. Check them out!
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Highlights of the 2009 meeting will include: SBE Biofuel Symposium: Transportation Fuels from Coal and Biomass: Review of an NRC Report, SBE James E. Bailey Award, SBE Hospitality Suite, Biology for Chemical Engineers Course, Chem-E-Car Competition: Best Use of a Biological Reaction to Power a Car.
www.earthtimes.org
NEW YORK - Scientists at the Polytechnic Institute of New York University report they have developed a novel method of stabilizing proteins, including important enzymes used to produce certain artificial sweeteners and bio-ethanol. The research will also be useful for extending the lifetime
Society for Biological Engineering (SBE)
About the Course
This course is designed to inform you about basic biology, biotechnology and pathology - all the essential elements to understand how biotechnologists come up with product ideas. You should attend if you are interested in learning about the science of biology and how it applies to the biotechnology ind...ustry. This course provides enough background to appeal to the novice biologist while bringing new research methods to the practicing engineer. Research managers, engineers, biochemists, scientists and students interested in biotechnology should attend.
Topics include:
-Cells, Viruses and Biomolecules
-Biotechnology - Tools and Products and Biomolecular Analysis
-Analyzing Complex Biological Systems
-The Immune System
-Diseases and Therapeutics
About the Course Instructor:
Dr. Michael Amos is the Biosciences Advisor to the Director of the Chemical Science and Technology Laboratory (CSTL), National Institute of Standards and Technology (NIST), Technology Administration, U.S. Department of Commerce. Dr. Amos received his B.S. degree in General Sciences from Virginia Commonwealth University, Richmond, Virginia and his Ph.D. in Basic Medical Sciences from the University of South Alabama, College of Medicine in Mobile, Alabama. His graduate area of emphasis was in microbiology and immunology and his thesis research was in regulation of the immune system. From there, he furthered his training at the University of Alabama at Birmingham, College of Medicine as a postdoctoral fellow in the Departments of Microbiology and Rheumatology, studying the molecular immunology of rheumatoid arthritis. He has held various industry research, marketing and business development positions in the fields of biopharmaceuticals, neutriceuticals, drug delivery, transgenics, immunodiagnostics, molecular biology and molecular pathology. He is also a founder of two biotechnology companies. Dr. Amos joined NIST in 2002 as a Program Manager and Biologist in the Chemistry and Life Sciences Office of the Advanced Technology Program (ATP), an extramural funding arm of NIST, established to accelerate private sector high-risk, high-reward technology development projects. At ATP, he managed projects on stem cells, nanotechnology, immunotherapeutics, cancer vaccines, neurobiology, protein therapeutics, drug discovery, gene therapy, metabolic engineering, and medical devices. Dr. Amos is a leader in the field of autoimmune immunodiagnostics and serves on the Autoimmune Disease Coordinating Committee of the National Institutes of Health. Mike joined CSTL in 2006, and serves as biosciences advisor to Dr. Willie May as a liaison to industry, academia and other government agencies in the bioscience and health care areas. Dr. Amos serves as the Department of Commerce representative on the HHS Secretaries Advisory Committee on Genetic, Health and Society and also participates on the NIH Autoimmune Diseases Coordinating Committee.
Note: Registration is available through the annual meeting online registration form – you DO NOT have to register for the annual meeting to register for this short course.
To register, please visit
http://www.aiche.org/SBE/Education/Cours
Time:8:00AM Sunday, November 8th
Location:Gaylord Opryland Hotel, Nashville, TN
Location:online
Time:2:00PM Thursday, October 22nd
