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Meta is an AI company specializing in big data analysis of scientific and technical literature.
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Elasticity allows spheres to walk on water. Jesse Belden et al...
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March 28

Scientists engineer atomic lattices with a predetermined electrical response by moving individual atoms. Illustrated is the tip of a scanning tunnelling microscope (STM) above chlorine atoms that have been deliberately moved.

Drost et al. Nature Physics 2017
Credit: Ella Maru Studio & Aalto University
Source: http://www.nature.com/…/j…/vaop/ncurrent/full/nphys4080.html

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March 27

Scientists discover that activating the host enzyme sirtuin 1 can reduce the growth of drug-susceptible and drug-resistant Mycobacterium tuberculosis, ameliorate lung pathology, and potentiate the efficacy of isoniazid in mice infected with M. tuberculosis. Shown is a macrophage (red) engulfing tuberculosis bacteria (yellow)

Cheng et al. Science Immunology 2017.
Credit: ZEISS Microscopy
Source: http://immunology.sciencemag.org/…/10.11…/sciimmunol.aaj1789

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March 23

Scientists reveal that lungs constitute a reservoir for megakaryocyte progenitor cells and blood stem cells, accounting for 50% of total platelet production. Shown is a confocal immunofluorescent micrograph of primary #megakaryocytes.

Lefrançais et al. Nature 2017.
Credit: Hornstein Lab.
Source: http://www.nature.com/…/journal/vaop/…/full/nature21706.html

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March 22

Scientists use genotyping data to devise a polygenic hazard score to identify and stratify risk for developing Alzheimer’s disease. Shown is a 3D reconstruction of an immune cell (red) containing β-amyloid (blue) within an intracellular degradation compartment (yellow).

Desikan et al. PLoS Medicine 2017.
Marie-Victoire Guillot-Sestier, PhD.
Source: http://journals.plos.org/plosmedicine/article…

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March 19

Scientists report that a single dose of inclisiran, PCSK9-specific RNA interference therapy, reduced participants’ LDL #cholesterol levels by 51 percent. Shown is an illustration of an atherosclerotic plaque deposit.

Ray et al. New England Journal of Medicine 2017
Credit: Intermountain Medical Center
Source: http://www.nejm.org/doi/full/10.1056/NEJMoa1615758…

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March 17

Scientists employ single-particle cryo-electron microscopy and mass spectrometry to uncover how the #cyanobacterial Kai system assembles to control the circadian clock. Shown are cyanobacterial cells.

Snijder et al. Science 2017.
Credit: Ducat Lab.
Source: http://science.sciencemag.org/c…/doi/10.1126/science.aag3218

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March 16

Scientists devise a paper-based #blood test that can determine blood type in seconds and with more than 99.9% accuracy. Shown is a computer graphics depiction of a human red blood cell on a glass surface.

Zhang et al. Science Translational Medicine 2017.
Credit: Rogeriopfm | Wikimedia Commons.
Source: http://stm.sciencemag.org/…/doi/10.1126/scitranslmed.aaf9209

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March 15

Scientists uncover 1.6 billion-year-old fossils of filamentous and lobate organisms that share numerous features with the modern eukaryotic red algae. Shown is an X-ray tomographic picture (false colors) of #fossil thread-like red algae.

Bengtson et al. PLoS Biology 2017
Credit: Stefan Bengtson
Source: http://journals.plos.org/plosbiology/article…

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March 14

Scientists create a phase of a matter, referred to as a time crystal, in which the atoms move in a regular rhythm in time rather than just in space. Shown is an artist’s rendering of this phenomenon.

Zhang et al. Nature 2017.
Credit: E. Edwards | JQI
Source: http://nature.com/articles/doi:10.1038/nature21429

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March 10

Scientists create a phase of a matter, referred to as a time crystal, in which the atoms move in a regular rhythm in time rather than just in space. Shown is an artist’s rendering of this phenomenon.

Zhang et al. Nature 2017
Credit: E. Edwards | JQI
Source: http://www.nature.com/…/jo…/v543/n7644/full/nature21413.html

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March 9

Scientists report that epalrestat, a drug that inhibits AKR1B1 and is used to treat diabetes, can be an effective therapeutic strategy against basal-like and triple-negative breast cancers. Shown is a breast #tumor (blue) using leader cells (green) to invade muscle tissue (red) in a mouse.

Wu et al. JEM 2017
Credit: Kevin Cheung
Source: http://jem.rupress.org/content/early/2017/03/06/jem.20160903

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March 7

Scientists discover that the antiprotozoal drug pentamidine can disrupt the outer cell surface of Gram-negative bacteria, enabling conventional antibiotics geared for Gram-positive bacteria to act against a wide array of superbugs such as Acinetobacter baumannii. Shown is a medical illustration of Acinetobacter.

Stokes et al. Nature Microbiology 2017
Credit: CDC
Source: http://nature.com/articles/doi:10.1038/nmicrobiol.2017.28

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March 7

Scientists demonstrate that heterogeneity of gut microbial communities in Caenorhabditis elegans is driven by the randomness of initial colonization events. Shown is bacteria (coloured orange) populating the digestive tract of the roundworm.

Vega et al. PLoS Biology 2017
Credit: Philipp Dirksen
Source: http://journals.plos.org/plosbiology/article…

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March 3

Scientists grow and differentiate mouse embryonic stem cell (ESCs) and trophectoderm stem cells (TSCs) into an elongated cylindrical structure resembling mouse embryos post implantation. Shown are stem cell-modeled mouse #embryo at 96h (left) and mouse embryo cultured in vitro for 48h from the blastocyst stage (right), with ESCs in red and TSCs in blue.

Harrison et al. Science 2017
Credit: Sarah Harrison and Gaelle Recher | Zernicka-Goetz Lab, University of Cambridge
Source: http://science.sciencemag.org/…/…/2017/03/01/science.aal1810

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March 2

Scientists use cryo-electron tomography to elucidate the molecular architecture of the nuclear #lamina in mammalian cells. Shown is the molecular organization of various components of the cell in their natural environment.

Turgay et al. Nature 2017
Credit: J. Mahamid | Max Planck Institute of Biochemistry
Source: http://www.nature.com/…/journal/vaop/…/full/nature21382.html

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Scientists report an increased incidence of subdural #hematoma in the Danish population that is associated with the use of antithrombotic agents, such as vitamin K antagonists or antiplatelet drugs. Shown are closely-packed polyhedral-shaped red blood cells in contracted clots.

Gaist et al. JAMA 2017
Credit: John Weisel | Perelman School of Medicine at the University of Pennsylvania
Source: http://jamanetwork.com/…/jama/fullar…/10.1001/jama.2017.0639

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