Ryan Landis, a graduate student in the Rotello group, was awarded $20,000 in seed money for the company he founded, Phytos Therapeutics, in the finals of the Innovation Challenge, a campus-wide entrepreneurial competition.
Congratulations Ryan for your achievement!!!
The number of bacteria that are gaining resistance to traditional antibiotics is rapidly increasing. Join Prof. Vince M. Rotello for a look at how nanomaterials provide an ‘outside the box’ alternative that shows considerable promise against these rapidly emerging pathogens. This new area of research is perhaps the most promising strategy to averting the health crisis threatened by antibiotic-resistant bacteria.
The delivery of proteins into cells is a potential game changer for a wide array of therapeutic purposes. In this review, Scaletti et al. discuss recently developed inorganic nanoparticle-protein supramolecular assemblies for protein delivery. Challenges in the field, particularly achieving effective cytosolic protein delivery through endosomal escape or evasion are discussed.
Hello, everyone!! The 7th Thesinge biofilm meeting
on biomaterial-associated infections is taking place on 1-2 october in Groningen. Prof. Rotello will be participating in the conference.
In order to participate, please use the attached application form or download it from: http://www.rug.nl/r…/biomaterials/7ththesingebiofilmmeeting/ and email to: email@example.com
Hello, everyone!! If you want to meet with Prof. Rotello, he will be participating in ACS on Campus India Roadshow events at University of Delhi (http://acspubs.co/77KI30i0ckt), IIT Roorkee (http://acspubs.co/andR30i0cku) and IISER Mohali ( http://acspubs.co/nOwb30i0ckv).
Registration is FREE! Network, promote your science (at one of the poster sessions) and hear great talks about research and publication!
What can be better building block for developing biomaterials than naturally abundant proteins? Imparting proteins molecular properties to materials surface is, however, challenging due to loss of protein structure upon film formation. In this work, Wang et. al. developed an additive-free and versatile method to fabricate functional protein coatings that retains protein charge, secondary structure, biodegradability and hydrophilicity.
Most of the transition metals catalysts (TMCs) lacks the solubility, stability, and activity in aqueous environment. This work by Jeong. et. al. describes a modular strategy to solubilize and stabilize different hydrophobic TMCs through the encapsulation of the catalysts into the monolayer of water-soluble gold nanoparticles. Beside bringing water solubility and providing a protecting environment for the catalyst, this platform is reusable without any lost in catalytic activity.
In this work the gold nanoparticle-CRISPR/Cas9 machinery is used to knock out the "don't eat me signal" in macrophages, allowing phagocytosis of cancer cells. Check out the paper by Ray. et. al. to know more about this integrated nanotechnology/biology approach to create 'weaponized' macrophages for cancer immunotherapy.
We all know that the structure of different biomaterials plays an important role in the activity. The functionality of these biological systems, such as, proteins, cell/bacterial membranes
are involved in many biological problems as well. In this article, Tullius. et. al. reports fingerprinting of Protein Interface Structure.
Rotello group has developed a general strategy to image bio-films that can rapidly "light-up" the infected mammalian cells. In this work, Gupta. et. al. fabricate NP-based systems that are stimulated by the altered micro-environment of bio-films.
Prof. Vincent M. Rotello explaining how nanomaterials are helping us in the fight against antibiotic resistant bacteria.
Check out the article!!